Blar i AURA på forfatter "Solbakken, Monica Hongrø"
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Evolutionary redesign of the Atlantic cod (Gadus morhua L.) Toll-like receptor repertoire by gene losses and expansions
Solbakken, Monica Hongrø; Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Seppola, Marit; Gregers, Tone Fredsvik; Jakobsen, Kjetill Sigurd; Jentoft, Sissel (Peer reviewed; Journal article, 2016)Genome sequencing of the teleost Atlantic cod demonstrated loss of the Major Histocompatibility Complex (MHC) class II, an extreme gene expansion of MHC class I and gene expansions and losses in the innate pattern recognition ... -
Linking species habitat and past palaeoclimatic events to evolution of the teleost innate immune system
Solbakken, Monica Hongrø; Voje, Kjetil L.; Jakobsen, Kjetill Sigurd; Jentoft, Sissel (Journal article; Peer reviewed, 2017)Host-intrinsic factors as well as environmental changes are known to be strong evolutionary drivers defining the genetic foundation of immunity. Using a novel set of teleost genomes and a time-calibrated phylogeny, we here ... -
Successive losses of central immune genes characterize the Gadiformes’ alternate immunity
Solbakken, Monica Hongrø; Rise, Matthew L.; Jakobsen, Kjetill Sigurd; Jentoft, Sissel (Journal article; Peer reviewed, 2016)Great genetic variability among teleost immunomes, with gene losses and expansions of central adaptive and innate components, has been discovered through genome sequencing over the last few years. Here, we demonstrate that ...